Boling Point | 220 °C(lit.) |
Storage Condition | Room Temprature |
Physical and Chemical Properties | Light brown or green volatile essential oil, with gum unique scorched sweet paste fragrance. It can be influenced by air and light to deepen and thicken the color. Soluble in most non-volatile oils, slightly soluble in mineral oils, insoluble in glycerol and propylene glycol. |
FEMA | 2765 | MYRRH GUM (COMMIPHORA SPP.) |
plant extract | The myrrh extract is a resin extract solidified after the discharge of the bark of plants such as the myrrh tree of the olive family and the ellburg myrrh tree, the main components were gum, resin and volatile oil. With blood stasis, swelling, analgesic effect. It is widely used in spices, cosmetics, food, medicine and health care products. |
Main component | resin containing 25% ~ 40% α-,β-,γ-practically acid common acid, α-,β-myrrh acid, α-,β-heeraborrhalic acid, α-,β-myrrh, heeraboresene, myrrh terpene alcohol (commiferin), etc. Essential oil 2.5% ~ 9% cumin aldehydes, eugenol, m-cresol (m-cresol), pinene, dipentene, limonene (limonene), myrcene (heerabo-lene), cinnamic aldehyde (cinnamic aldehyde), formic acid (formic acid), acetic acid (acetic acid)-, gums such as β-,γ-bisabolene) 57%-65% are decomposed into arabinose, galactose, xylose and the like by adding water. |
source plant | [base source] cured resin from the bark wound of plants such as the olive plant myrrh tree and ellburg myrrh tree. Pharmacognosy collects coagulum of resin that flows out or naturally flows out of a wound after artificial manufacture. Generally taken in winter. myrrh can be divided into the following types according to its original plant and origin: Somal myrrh (Somal myrrh;Heerabol myrrh) is a red resin of C.molmol, first-class. It is mainly produced in the island of Somalia in Eastern Africa, and is exported to Europe directly or via Bombay after being transported to Adden. China also imports from Bombay, Japan imported through Bombay or Hong Kong, the so-called "all myrrh" is almost this product. Arabian myrrh (Fadhli myrrh): derived from the native Ethiopia myrrh of Southern Arabia and Ethiopia. abyssinica (Berg.) engl. And C.schimperi (Berg.) engl., it is in the form of a small aggregate, with less fragrance and bitterness than Somalis myrrh. Yemen myrrh: dark red, large mass. The bitterness and aroma are similar to Somal myrrh, but the aroma is insufficient. [distribution] varies with species, occurring in southern Arabia, Ethiopia, Somalia Island, India, etc. [specification] myrrh is irregular granular mass, varying in size, red-brown or yellow-brown, rough surface, covered with dust. Characteristics of myrrh: sometimes surrounded by dog skin or in the shape of a cake, firm and brittle, easy to break up, granular, with brown oil-like luster, translucent. Dog skin myrrh was tan or yellow-brown, rubbery, not easy to crack, opaque. Co-studied with water to form a yellow emulsion. It is slightly aromatic, with slightly bitter taste. those with large size, red-brown color, strong fragrance and no impurities are preferred. Figure 1 is myrrh |
pharmacological activity | pharmacology of traditional Chinese medicine nature and flavor: bitter, Xin, Ping. Meridian tropism: heart, liver and spleen meridian. function: activating blood circulation to relieve pain, reducing swelling and generating muscles, aromatic flavor and fragrance, able to walk and act well, so it can promote blood circulation and Qi, blood and qi, and stop pain, therefore, there is this work. pharmacological effects Anti-tumor effects: myrrh extract can be used for the prevention and treatment of breast cancer and prostate cancer. The anti-cancer effect of myrrh is not only stronger than the commonly used chemotherapy drugs, but also safer, because the myrrh extract only kills cancer cells and has no effect on normal cells and does not produce drug resistance. Anti-fungal and anti-inflammatory effects: the water decoction of myrrh has different degrees of inhibition on various pathogenic dermatophytes in vitro, hamus et al reported that several active ingredients with a strong anti-inflammatory effect were isolated from the resin secreted by myrrh tree grown in Kenya, Africa, and one of them was called manzurinic acid, it has a good inhibitory effect on acute inflammation or chronic inflammation, and has a strong inhibitory effect on peroxidase, the main substance causing inflammation in vivo. analgesic effect: Italian scientists extracted three kinds of sesquiterpene components from Myrrh. Animal experiments have proved that at least two components have strong analgesic effect. They injected the mice at a dose of 1.25 mg per kilogram of body weight, and the mice were able to withstand the baking of burning iron plates. The mice were orally administered at a dose of 50 mg/kg body weight, and the mice could tolerate the pain caused by severe abdominal muscle spasm caused by acetic acid injection. neuroprotective effect: Jing Xu et al. myrrha (India) isolated four new sesquiterpenoids showing neuroprotective effects, in particular, inducing the death of MMPs in human neuroblastoma cells, with guanine being used as a positive regulation of the lactose operon. Neuroblastoma exposed to MMP its viability was detected by MTT assay, the control experiment, there was significant difference (P<0.01). coagulation effect: the water extract and volatile oil of myrrh can produce significant effects on rabbit platelet aggregation and thrombin time. other effects: myrrh extract can reduce cholesterol and protect stress ulcer. |
extraction method | the extraction methods of myrrh extract mainly include CO2 extraction, Soxhlet extraction, ultrasonic extraction and steam distillation, the components of the extracts obtained by each extraction method are very different, and there are many chemical components and types in the CO2 extract. In addition to the volatile oil, there are a large number of effective components such as resins, CO2 extraction method can avoid high temperature and residual organic solvent in the extraction process, and CO2 extraction method is suitable for the extraction of myrrh. |
identification | 1. Identification of UV spectrum ① UV spectrum of myrrh: take sample 0.1g, add ethanol 20ml, ultrasonic extract 10min, filter, the filtrate was diluted with ethanol to a solution containing UV-160A mg of the medicinal material per ml, and the ultraviolet spectrum was measured on a Shimadzu spectrophotometer in the wavelength range of 200-400nm. Results The UV spectra of natural myrrh and colloidal myrrh were similar. Figure 2 is the UV spectrum of myrrh figure 1. Natural myrrh 2. Colloidal myrrh ② UV spectrum of myrrh and its counterfeit: take sample coarse powder 0.5g, add methanol 5ml, soak for 24h, filter, measure the UV spectrum of filtrate. Results The Lambda maxMeOH of natural myrrh was 207.0nm, the Lambda maxMeOH of colloidal myrrh was 267.0nm, and the lambda maxMeOH of rosin pseudo-product was 241.0nm. FIG. 3 is the ultraviolet spectrum of myrrh and its counterfeit. Natural myrrh 2. Gliadin 3. The first derivative UV spectrum of myrrh: Take "1." under the sample liquid, according to the law to determine the first derivative UV spectrum. Results natural myrrh and colloidal myrrh had a characteristic peak at 242±2nm wavelength. FIG. 4 is the UV first derivative spectrum of myrrh. Natural myrrh 2. Gliadin 2. Infrared spectrum identification take the sample solution under the item of "ultraviolet spectrum identification -2", concentrate it, and measure its infrared spectrum by coating method. Results The infrared spectra of natural myrrh, colloidal myrrh and rosin pseudo-products were different. Figure 5 is the infrared spectrum of myrrh and its Counterfeit. Figure 1. Natural myrrh 2. Colloidal myrrh 3. Rosin counterfeit |
processing method | ." St. N.: "File as soap." "Hong's collection and prescription": "Research for the end." "Health heirth obstetrics": "to stone." "The Great Law": "or with the mortar sitting hot water in the milk, the cloud is easy to fine." "Four orders of physicians": "Water flying research." Currently, take the original medicine, remove impurities, mash or chopped. 2. Fried myrrh original herbal medicine: "into the pill scattered, micro-fried on bamboo leaves, disinfection is not sticky." "Shoushi Baoyuan": "stir-fried with micro-heat in a sand pot, produce smoke, and fine study." "Yutan medicine solution": "Fried dry research." At present, the samples were separated from each other and placed in the pan. When the surface was oily and glossy, they were placed for cooling. 3. Vinegar and myrrh were separated from each other and placed in the pan. The mixture was gently fried until smoking, with slightly melted surface. Myrrh per 100, with vinegar 5kg. 4. The "law of cooking": "to study with the heart of the lamp." "Collection of surgical syndrome and treatment for whole life": "stir-fried every kg with the heart of four or two lamps, stir-fried until round and brittle can be flour for degree, fan to remove the heart of flour." "Paris polyphylla": "stir-fried to remove oil." At present, take the purified pieces of myrrh, place them in the pan, stir-stir them with gentle fire until the oil is extracted, stir-stir them with the addition of the lamp heart, until the oil is completely absorbed by the lamp heart, and the myrrh bulges into a spherical shape, cool. Myrrh every 100kg, with the lamp heart 3kg. 5. After boiling the myrrh, take the myrrh, soak it in water for 1 day, pour it into the pan with water, boil it until it melts, filter it, boil the residue with an appropriate amount of water, filter it, discard the residue, combine the filtrate and concentrate it into paste, when heating was continued until black smoke turned into smoke, it was taken out and placed on a flat plate. |
Use | for stomach, Meridian, strong medicine. But now Japan as a convergence medicine, for brushing, gargle water, in the form of myrrh tincture use. Also used in the fragrance industry. GB 2760-96: permitted use of food flavors. |
production method | produced by some species of myrrh in the olivaceae family (C.myrrha et al.) the obtained bisabolol gum resin was obtained by steam distillation. The yield ranged from 3% to 8%. It is mainly produced in Ethiopia, Somalia and the United States. |